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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
11.5 DPC

9 matching records from 9 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mesp2  mesoderm posterior 2   (Synonyms: bHLHc6)
Results  Reference
1*J:220849 Achilleos A, Huffman NT, Marcinkiewicyz E, Seidah NG, Chen Q, Dallas SL, Trainor PA, Gorski JP, MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development. Hum Mol Genet. 2015 May 15;24(10):2884-98
1*J:122747 Chan T, Kondow A, Hosoya A, Hitachi K, Yukita A, Okabayashi K, Nakamura H, Ozawa H, Kiyonari H, Michiue T, Ito Y, Asashima M, Ripply2 is essential for precise somite formation during mouse early development. FEBS Lett. 2007 Jun 12;581(14):2691-6
1J:178365 Cunningham TJ, Zhao X, Duester G, Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension. Genesis. 2011 Oct;49(10):776-83
1*J:75945 Nomura-Kitabayashi A, Takahashi Y, Kitajima S, Inoue T, Takeda H, Saga Y, Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis. Development. 2002 May;129(10):2473-81
1J:42014 Saga Y, Hata N, Koseki H, Taketo MM, Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 1997 Jul 15;11(14):1827-39
1J:167045 Sasaki N, Kiso M, Kitagawa M, Saga Y, The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis. Development. 2011 Jan;138(1):55-64
1*J:161418 Takahashi J, Ohbayashi A, Oginuma M, Saito D, Mochizuki A, Saga Y, Takada S, Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite. Dev Biol. 2010 Jun 15;342(2):134-45
1J:78989 Takahashi Y, Koizumi K, Takagi A, Kitajima S, Inoue T, Koseki H, Saga Y, Mesp2 initiates somite segmentation through the Notch signalling pathway. Nat Genet. 2000 Aug;25(4):390-6
1*J:208899 Williams DR, Shifley ET, Lather JD, Cole SE, Posterior skeletal development and the segmentation clock period are sensitive to Lfng dosage during somitogenesis. Dev Biol. 2014 Apr 15;388(2):159-69

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory